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Clinical research in the field of brain tumors in the Bioinformatics department

The Bioinformatics department runs its own line of research. This study studies the genome and the way in which the genome as a whole contributes to hereditary congenital facial abnormalities and cancer in the brain. This provides the basic biological and technical knowledge for all bioinformatics activities. In addition, the department is looking for new ways to realize healthcare innovation in collaboration with healthcare insurers.

Patient Stratification
The department collaborates in public private partnerships with companies such as Skyline Diagnostics for the development of translational molecular diagnostic tests and valorisation of research investments. The new diagnostic tests for personalized healthcare applications are made with resources from CTMM and future Top Sector policy. Work is being done on all types of cancer, including brain cancer, in collaboration with the Brain Tumor Center.

Bioinformatics: Data Mining
Researchers and doctors find themselves confronted with increasing amounts of data from research and patient care. Interpretation and analysis of these biomedical data is increasingly becoming a multidisciplinary matter. The Bioinformatics department helps researchers to quickly analyze, contextualize and store their data by applying state of the art IT. Particularly in the field of genome diagnostics we are dealing with so-called “big data”. The ErasmusMC Bioinformatics department has developed a strategic partnership with the American IT company Oracle. This includes Roche, Merck, Inova, and the Moffitt Cancer Center for the joint development of translational research infrastructure.

Molecular Imaging
New visualization methods make it possible for clinicians to view and discuss ultrasound images, CT scans and MRI scans for diagnostic purposes pre-operatively in 3D. In addition, any protein or messenger RNA molecule can be visualized in vivo by whole mount staining in tumor tissue or whole embryos for research purposes.